Current Clinical Trials

Posted February 2019

Well-Being and Health in RLS

Restless Legs Syndrome (RLS) is a condition associated with significant lifestyle changes. Researchers at Yale University are conducting a study that looks at health and well-being in patients with RLS. The researchers are looking to study primary RLS, which is RLS that occurs in the absence of diseases like Parkinson’s disease, multiple sclerosis, severe neuropathy, end-stage renal disease, schizophrenia, terminal cancer, and others. The study is a one-time online questionnaire that takes about 10–20 minutes to complete. You will not need to talk to anyone to complete this study, and your response is completely anonymous. There is no way for the researchers or anyone to determine your identity, even after you have completed the questionnaire.

To participate:

  • Follow this link to the survey: https://yalesurvey.ca1.qualtrics.com/jfe/form/SV_4I7rXK9CXrA7wwt
  • The first page contains information about how data is collected and stored. Selecting “I consent to participate in this research study” will initiate the survey.
  • Please read all instructions carefully to ensure that questions are answered appropriately.
  • Most of the questions require a response. Do not skip any sections unless instructed to do so. You will be informed if you accidentally skip a required question.
  • The survey should be completed in one sitting.

Contacts: If you have questions, please contact Nada Ahmed at nada.ahmed@yale.edu

Posted October 2018

RLS & My Teen: What’s Next? — Fight RLS with Science

Is it really tough to get to sleep sometimes? Find out about a study that’s for adolescents dealing with RLS. Sometimes, RLS is often misdiagnosed with a with range of issues, including growing pains or behavioral problems—and that can be tough on everyone around them. Now your child can participate in a study for 13–17-year-olds with RLS. This study is open to those with RLS and living in California, Florida, Illinois, New Jersey, New York, and Texas. Compensation available.

Visit: www.science37.net/rls-teens
Call: (310) 464-2190
Email: RLSstudy@science37.com

Posted December 2017

Opioid Use to Treat RLS

Dr. John Winkelman is building an RLS Opioid Registry based at Massachusetts General Hospital with patients from across the United States to assess the long-term safety and effectiveness of opioid medications for RLS.

The RLS Opioid Registry will collect information from people who have been diagnosed with RLS and are taking a prescribed opioid as a treatment for symptom management. An initial brief phone interview will be followed by online surveys every 6 months for at least five years. Participants will be provided with a personal and full-sample summary of the data on a yearly basis. All data is stored anonymously in a secure electronic database.

Enrollment is limited to individuals who meet all the following criteria:

  • a diagnosis of RLS
  • are taking an opioid medication for RLS
  • have taken (or are currently taking) a dopamine agonist for RLS

Call: Julia Purks, (617) 643-2082
Email: RLSregistry@partners.org
Visit: www.massgeneral.org/rls-registry

Note: We will not be providing any consultation, advice about clinical care, or medication through this study.

 

 

Posted March 2016

Does your child have discomfort in their legs that may interfere with their sleep? They may describe their symptoms as throbbing, pulling, creeping, pain or other abnormal sensations felt in the legs when lying down or sitting. Your child may be suffering from adolescent Restless legs Syndrome.

Worldwide Clinical Trials is conducting research studies to test an investigational medication for the treatment of adolescent RLS. You will receive the medication at no charge, an assessment by an RLS expert and compensation for participating in this research clinical trial. The studies will take place at the following locations Amherst (NY), Columbia (SC), Indianapolis (IN), Nashville (TN), Philadelphia (PA), Redwood City (CA), and San Diego (CA). Qualified participants will be compensated for time and travel. To qualify, participants must:

  • be 13-17 years of age
  • be diagnosed with RLS
  • have moderate-to-severe symptoms
  • have parent/legal guardian consent

If you are interested in learning more about this study, or to find out if you qualify call (520)-252-1908 or email Camilla.Alexander@wwctrials.com.

Posted January 2013

If you live in the New York City area, you may be eligible to participate in a new research opportunity.

We are conducting a research study to determine whether there are changes in the retinal structure of the eyes of individuals with Restless Legs Syndrome, also known as Willis-Ekbom Disease (WED/RLS) compared to individuals with Parkinson’s disease, multiple system atrophy, and healthy controls.

The study will take place at the New York University Langone Medical Center and will require one visit, lasting approximately 1-2 hours. The visit will include an initial screening and an eye exam. You will be asked to sit comfortably and to place your chin in a chin rest and to look into a machine that will take pictures of your optic nerve. The eye examination will take approximately 15 minutes and you will not feel anything while the machine takes pictures of your retina (the back of your eye).

There is no direct benefit to you or expense reimbursement available from your participation in the study. It is hoped that the knowledge gained will be of benefit to others in the future. Studies done for this research study are not a part of your regular medical care and will not be included in your medical record.

If interested, please contact Dr. Jose Martinez at Jose.Martinez@nyumc.org.

Further Reading

Clinical Trails: What to Know Before You Go

Inside: Important Information for those considering clinical trail participation

Read More