Medical & Scientific Info

Medical & Scientific Info

RLS Foundation Research Grant Program

 

Funding

Through its annual research program, brain and tissue collection program, and support of clinical trials, the RLS Foundation honors promising scientists whose work addresses the goals of the RLS Foundation. Grants and fellowships are awarded by the RLS Foundation Scientific Advisory Board on a competitive basis with applications ranked on scientific merit by a panel of leading scientists in the field.  

Below, is a listing of current and past recipients of Foundation research grants.

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RESEARCH GRANT AWARDS 2012
 

Stephanie Patton, PhD
The role that the nitric oxide pathway plays in regulating vasodialation of the legs in Restless Legs Syndrome.
The Pennsylvania State University College of Medicine

Yuan-Yang Lai, PhD
Effect of histamine H3 receptor antagonism on PLM in iron-deficient rats: an animal model of RLS and its treatment. 
University of California Los Angeles and Sepulveda Research Corporation
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RESEARCH GRANT AWARDS 2011

Subhabrata Sanyal, Ph.D

Genetic modeling of Restless Legs Syndrome in Drosophila

Emory University School of Medicine, Atlanta, GA

 

Padmavathi Ponnuru, PhD

A role for MEIS1 in brain iron deficiency in Restless Legs Syndrome  

Drexel College of Medicine

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RESEARCH GRANT AWARDS 2009
 
 
Stephanie Miller Patton, PhD
The role that the hypoxia response pathway & neuronal nitric oxide synthase (nNOS) plays in the mechanism of RLS

Pennsylvania State University College of Medicine, Hershey, PA 
 
Lan Xiong, MD, PhD
Genome wide gene expression profile & iron regulation in RLS patients carrying the MEIS1 genetic risk variant
McGill University, Montreal, Canada
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RESEARCH GRANT AWARDS 2008
 
Juliane Winkelmann, MD
Worldwide genome-wide association study for RLS: WW-GWA-RLS
Institute of Human Genetics

GSF National Research Center, Munich, Germany

 

Guy Rouleau, MD, PhD
Defining the risk variants within the MEIS1, BTBD9, MAP2K5/LBXCOR1 genomic regions in RLS patients

Human Research Centre
Notre Dame Hospital, Montreal, Quebec

 

David B. Rye, MD, PhD
RLS genome study - USA/ICELAND
Emory University School of Medicine, Atlanta, GA
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RESEARCH GRANT AWARDS 2006

 
Douglas E. Wright, PhD
Contributions of Abnormal Sensory Input from Muscle in RLS
The University of Kansas Medical Center, Kansas City, KS
 
Stephanie Patton PhD
The contributory role that iron-sulfur cluster proteins play in RLS 
Pennsylvania State University College of Medicine, Hershey, PA
 
 
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RESEARCH GRANT AWARDS 2005  
 

Jeffrey Durmer, MD, PhD

Identification of restless legs syndrome in children

Emory University School of Medicine, Atlanta GA

 

 

 

Stephanie Miller Patton, PhD

The contribution of iron regulatory proteins (IRPs) to the

dysregulation of iron hemeostasis in RLS

Pennsylvania State University

MS Hershey Medical Center, Hershey, PA

 

Juliane Winkelmann, MD

EU-RLS-GENE – Three loci for RLS on chromosome

12q (RLS-1); 14q (RLS-2); and 9p (RLS-3) mapping study

Institute of Human Genetics

GSF National Research Center

Munich, Germany

 

 

Lorene M. Nelson, PhD and Stephen Van Den Eeden, PhD

Pilot study of restless legs syndrome in Kaiser Permanente

Stanford University School of Medicine, Stanford, California

Kaiser Permanente Division of Research, Oakland, California

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RESEARCH GRANT AWARDS 2004

 

Byron C. Jones, PhD
The Pennsylvania State University, University Park, PA

"Proposal to create mouse colony to identify candidate genes related to RLS"

 

 

Lorene Nelson, PhD

Stanford University School of Medicine , Stanford CA

Pilot Study of Restless Legs Syndrome in Kaiser Permanente

 

 

Seiji Nishino MD, PhD

Stanford Center for Narcolepsy Research, Palo Alto CA

PLMS in hypocretin-deficient narcoleptic dogs

 

David Rye, MD, PhD          

Emory University School of Medicine, Atlanta GA

Neural substrates of and pharmacologic interventions for restless legs  syndrome and paroxysmal limb movements during sleep (year 2)

 

Karin Stiasny-Kolster, MD

Department of Neurology, Marburg Germany

Quantitative sensory testing (QST) in RLS

 

Stephen V Van Den Eeden PhD

Kaiser - Division of Research, Oakland CA

Pilot Study of Restless Legs Syndrome in Kaisier Permanente

 

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RESEARCH GRANT AWARDS 2003

James R Connor PhD
Penn State Milton S. Hershey Medical Center, Hershey, PA
Is Defective Transferrin Receptor Expression in the brain the underlying cause of RLS?

Shawn Hochman PhD
Emory University School of Medicine, Atlanta, GA
Spinal Dopamine Dysfunction and Restless Legs Syndrome

Lan Xiong
McGill University, Montreal, Canada
Dissecting Genes Involved in Restless Legs Syndrome in French-Canadian Population with Elevated Prevalence

Lorene Nelson PhD

Stanford University School of Medicine , Stanford CA

Pilot Study of Restless Legs Syndrome in Kaiser Permanente

 

 

David Rye, MD, PhD          

Emory University School of Medicine, Atlanta GA

Neural substrates of and pharmacologic interventions for restless legs  syndrome and paroxysmal limb movements during sleep (year 1)

 

Stephen V Van Den Eeden, PhD

Kaiser - Division of Research, Oakland CA

Pilot Study of Restless Legs Syndrome in Kaisier Permanente

 

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RESEARCH GRANT AWARDS 2002

David B. Rye, MD, PhD
Emory University School of Medicine, Atlanta GA
Genetic linkage analysis of RLS in Iceland (Year 2)

Yuan-Yang Lai, PhD,
University of California, Los Angeles, North Hills CA
Ventral mesopontine junction mediated muscle activity during sleep

Felipe Espinosa, DVM, PhD
UT Southwestern Medical Center
Potential mouse model for human-RLS (hRLS) (Year 2)

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RESEARCH GRANT AWARDS 2001

James R. Connor, PhD
The Pennsylvania State University
Elucidating mechanisms for regulation of iron acquisition by the brain

Christopher J. Earley, MD, PhD
JHU Bayview Medical Center
Epidemiological study of an elderly twin cohort

Felipe Espinosa, DVM, PhD
UT Southwestern Medical Center
Potential mouse model for human-RLS (hRLS)

David B. Rye, MD, PhD
Emory University School of Medicine
Genetic linkage analysis of RLS in Iceland (Year 1)

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RESEARCH GRANT AWARDS 2000

William Ondo, MD
Baylor College of Medicine
For assistance with the Harvard Brain Tissue Resource Center

Judith Owens, MD, MPH
Brown University School of Medicine
Restless leg and periodic limb movements in children with iron deficiency anemia and elevated lead

Michael Polydefkis, MD
The Johns Hopkins University School of Medicine
A Trial of gabapentin in RLS stratifying patients by presence/absence of small fiber neuropathy

David B. Rye, MD, PhD
Emory University School of Medicine
Fellowship for Drs. Amanda Freeman and Glenda Keating - Non-human primate model of PLMS

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RESEARCH GRANT AWARDS 1999

William Bara-Jimenez, MD
National Institute of Neurological Disorders and Stroke Fellowship

Judith Owens, MD, MPH
Brown University School of Medicine
Restless leg and periodic limb movements in children with iron deficiency anemia and elevated lead

Guy Rouleau, MD, PhD
Montreal General Hospital Research Institute
Searching for genes predisposing to restless leg syndrome in the French-Canadian population

David Eidelberg, MD

NorthShoreUniversityHospital
A quantitative whole-brain imaging study of the dopamine transporter in the RLS using FP-betaCIT PET Scanning

 

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RESEARCH GRANT AWARDS 1998

 

William Bara-Jimenez, MD
National Institute of Neurological Disorders and Stroke Fellowship

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RESEARCH GRANT AWARDS 1997

William Bara-Jimenez, MD
National Institute of Neurological Disorders and Stroke Fellowship

 

 

 

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