About RLS
Clinical trials recruitment
Current RLS clinical trials are listed below. Please contact the institution and investigators directly if interested in participating in the clinical trial. All studies have received IRB (Institutional Review Board) approval which allows us to make sure that all studies listed on our site are legitimate.
Also, The RLS Foundation has partnered with the Center for Information & Study on Clinical Research Participation (CISCRP) to provide easier access to Restless Legs Syndrome clinical trials information with this search tool, increasing awareness about investigational treatments available. This information is offered by SearchClinicalTrials.org, a search engine for clinical trials information. Click here to use this search engine.
If you have a study you would like to have listed on our site, please email rlsfoundation@rls.org. Our listings are free, however, all studies must have IRB approval to be listed.
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November 2009
Research on Restless Legs Syndrome: Have you ever been diagnosed by a physician with RLS? If so, you may be eligible to participate in a Web survey about RLS and how RLS affects your life. Participants may receive up to $50 in Amazon.com gift certificates for participating. For more information, please visit www.rlssurvey.com.
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October 2009
When you try to relax or sleep, do you ever have unpleasant restless feelings that can be relieved only by walking or movement? If so, you may qualify for a research study that is looking for a new way to diagnose Restless Legs Syndrome. Involvement in this research study does not require taking new medications. Qualified participants will be reimbursed $250. The study takes place in the Philadelphia, PA area. If you are interested, please email: jdicarlo@abramsoncenter.org or call 215-371-1896
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September 2009
If you are a licensed driver age 21 to 65 and have RLS, you may qualify for a study. Call today for more information: 1-877-5-STUDY-9.
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July 2009
Jerking. Twitching. Fidgeting. That's how your legs may feel if you have restless legs syndrome (RLS)-a condition that makes your legs very uncomfortable when relaxed. The condition can interfere with both sleep and daily activities; this research study is evaluating a medication for restless legs syndrome. Qualified participants must:
· be at least 18 years of age
· experiencing RLS symptoms
· have trouble sleeping due to RLS
Please call 404-851-9934 or visit www.neurotrials.com.
You may be eligible to participate in a research study at University Hospitals Case Medical Center if you have RLS and are at least 18 years of age. We are investigating the possible relationship between RLS and mutations in a skin protein gene which commonly occurs in Caucasians. For this reason we are studying only Caucasians with RLS. Other exclusionary criteria may also apply. If you are interested, please contact Brian Koo, M.D. at (718) 813-9422. The medical center is in the Cleveland, Ohio area.
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June 2009
RLS RESEARCH STUDY: Tugging, burning, creepy-crawly? Discomfort or pain in your legs? Visit www.rls-study.com
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May 2009
Are you an RLS Patient who Switched to Ropinirole From Pramipexole? The purpose of this study is to determine the equipotent dose of ropinirole and pramipexole for patients switched from pramipexole to ropinirole in patients with moderate to severe primary Restless Legs Syndrome (RLS). The rationale behind Switch is that patients with Restless Legs Syndrome can maintain stable efficacy and tolerability if correctly switched from one dopamine agonist to an equipotent dose of another. Go to http://clinicaltrials.gov/show/NCT00344994 for details.
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April 2009
Do you experience an uncomfortable sensation in the legs, accompanied by an irresistible URGE TO MOVE YOUR LEGS, which is worse at night? Have these symptoms disrupted your sleep at least 3 nights per week for the past 3 months? You may be eligible to participate in a research study of an investigational medication intended to help control the urge to move your legs. As a qualified participant, you may receive: • Investigational medication • Study-related exams • Up to $200 in compensation for your time and transportation To participate, you must: • Be 18 to 85 years of age • Experience symptoms of RLS. Contact: TIMOTHY L. GRANT, M.D. • HOWARD I. SCHWARTZ. M.D. BOARD CERTIFIED PHYSICIAN. For more information, please call: (305) 279-0015 Ext. 4238. Location: 141 Sunset Dr., Suite 301, So. Miami.
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March 2009
If your RLS symptoms occur at least three times a week and you are over 18 please contact Broward Research Group 954-322-1600 or mgonzalez@browardresearch.com.
Coastal Clinical Research is conducting a study of an investigational medication to relieve symptoms of RLS. Study participants must be 18 or older and have moderate to severe RLS. Other criteria apply as well. Qualified participants will receive at no cost, study related medical exams, study medication, and compensation for time and travel. Please note that this study is for individuals in the Mobile, AL area. For more information contact Amanda Rowe at 251-414-1984 (www.CoastalClinicalResearch.com).
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October 2008
Wake Research is conducting a study of an investigational medication to see if it helps improve the sleep in adults with RLS. Study participants must be 18 or older, have RLS, and have trouble sleeping due to RLS. Other criteria apply as well. Qualified participants will receive at no cost, study related medical exams, study medication, and compensation for time and travel. Please note that this study is for individuals in the Raleigh, North Carolina area. For more information contact Jonathan Flescher, MD at 919-781-2514 (www.wakeresearch.com).
A nationwide team of researchers is investigating a medicine for RLS. This study will assess the safety and effectiveness of an investigational medication compared to a placebo (a substance which contains no active medication) in adults 18 years or older with RLS. About 114 people will participate in this study at approximately 28 research centers throughout the U.S. If you qualify to participate you will receive (at no cost) healthcare monitoring as it relates to the clinical study, study-related medical care, comprehensive sleep testing, and study medication. For more information and to find a study center near you, please visit: www.rlssleepstudy.org.
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September 2008
Do your legs have a mind of their own? Study participants will receive (at no cost): study-related exams and investigational study medicine. Call 1-800-617-4922 to see if you qualify.
If you live in the San Diego vicinity, please call 1-877-927-5337 for details on this study.